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В модели загорается MN9, моторный нейрон хоботка: ровно это Шиу и соавторы проверили в опыте."},"stim":20,"active":417,"spikes":15764,"trials":10,"ignited":0,"top":[{"i":314,"type":"CB0700","cls":"motor","side":"left","hz":205.9},{"i":36860,"type":"CB0700","cls":"motor","side":"right","hz":199.4},{"i":36791,"type":"MNx01","cls":"motor","side":"right","hz":178.3},{"i":8884,"type":"CB0248","cls":"central","side":"right","hz":174.2},{"i":34282,"type":"CB0248","cls":"central","side":"left","hz":155.1},{"i":10666,"type":"DNge031","cls":"descending","side":"left","hz":145.4},{"i":43985,"type":"CB0192","cls":"central","side":"left","hz":144.1},{"i":3101,"type":"CB0118","cls":"central","side":"left","hz":136.1},{"i":35201,"type":"CB4055","cls":"central","side":"left","hz":134.3},{"i":36301,"type":"CB0910","cls":"central","side":"right","hz":130.7},{"i":35810,"type":"CB4055","cls":"central","side":"right","hz":129.1},{"i":6214,"type":"CB0020","cls":"central","side":"left","hz":122.0},{"i":43893,"type":"CB0445","cls":"central","side":"left","hz":121.7},{"i":36293,"type":"MN10","cls":"motor","side":"right","hz":120.2}],"keys":[{"i":393,"kind":"MN9","label":{"en":"MN9 — proboscis motor neuron","ru":"MN9 — моторный нейрон хоботка"},"side":"right","hz":95.2}],"by_class":{"sensory":26,"descending":73,"central":278,"motor":28,"visual_centrifugal":6,"ascending":6},"bytes":101928},{"id":"bitter","icon":"🍋","rate":150,"label":{"en":"Bitter","ru":"Горечь"},"what":{"en":"21 bitter-sensing taste neurons","ru":"21 горький вкусовой рецептор"},"expect":{"en":"Bitter stops feeding: in Shiu et al. it silences MN9 even when sugar is given at the same time.","ru":"Горечь тормозит питание: в опыте Шиу она гасит MN9, даже когда одновременно дают сахар."},"stim":20,"active":80,"spikes":4603,"trials":10,"ignited":0,"top":[{"i":4760,"type":"CB0159","cls":"central","side":"left","hz":169.1},{"i":36194,"type":"CB0159","cls":"central","side":"right","hz":167.4},{"i":7021,"type":"CB0219","cls":"central","side":"left","hz":123.5},{"i":35680,"type":"CB0099","cls":"central","side":"left","hz":80.4},{"i":7269,"type":"CB2355","cls":"central","side":"left","hz":76.0},{"i":35843,"type":"CB0254","cls":"central","side":"left","hz":65.8},{"i":36256,"type":"CB0219","cls":"central","side":"right","hz":65.4},{"i":6801,"type":"CB0211","cls":"central","side":"left","hz":60.1},{"i":12927,"type":"CB0812","cls":"central","side":"left","hz":58.7},{"i":150,"type":"CB0963","cls":"central","side":"left","hz":41.1},{"i":35939,"type":"AVLP445","cls":"central","side":"left","hz":38.6},{"i":35498,"type":"CB0101","cls":"central","side":"left","hz":37.0},{"i":28873,"type":"DNge067","cls":"descending","side":"left","hz":36.2},{"i":33140,"type":"CB2388","cls":"central","side":"left","hz":35.9}],"keys":[{"i":393,"kind":"MN9","label":{"en":"MN9 — proboscis motor neuron","ru":"MN9 — моторный нейрон хоботка"},"side":"right","hz":0.0}],"by_class":{"sensory":20,"endocrine":2,"ascending":5,"central":46,"descending":7},"bytes":32268},{"id":"water","icon":"💧","rate":150,"label":{"en":"Water","ru":"Вода"},"what":{"en":"18 water-sensing taste neurons","ru":"18 водных вкусовых рецепторов"},"expect":{"en":"A thirsty fly drinks: water, like sugar, drives MN9 and the proboscis — through different interneurons.","ru":"Жаждущая муха пьёт: вода, как и сахар, тянет к MN9 и хоботку, но через другие промежуточные нейроны."},"stim":18,"active":267,"spikes":6108,"trials":10,"ignited":0,"top":[{"i":34022,"type":"CB0062","cls":"central","side":"left","hz":151.7},{"i":30967,"type":"CB0407","cls":"central","side":"left","hz":151.3},{"i":36760,"type":"VP5+Z_adPN","cls":"central","side":"left","hz":139.3},{"i":217,"type":"CB0008","cls":"central","side":"left","hz":121.3},{"i":43985,"type":"CB0192","cls":"central","side":"left","hz":115.0},{"i":34828,"type":"CB0008","cls":"central","side":"right","hz":107.9},{"i":31758,"type":"DNg67","cls":"descending","side":"left","hz":102.2},{"i":9400,"type":"CB0296","cls":"central","side":"left","hz":101.0},{"i":40737,"type":"AN_GNG_30","cls":"ascending","side":"left","hz":96.6},{"i":31060,"type":"CL133","cls":"central","side":"left","hz":96.1},{"i":34912,"type":"DNg67","cls":"descending","side":"right","hz":79.7},{"i":36239,"type":"CB0579","cls":"central","side":"left","hz":75.0},{"i":9461,"type":"LHPV6l2","cls":"central","side":"left","hz":69.1},{"i":43397,"type":"LHAD4a1","cls":"central","side":"left","hz":69.1}],"keys":[{"i":393,"kind":"MN9","label":{"en":"MN9 — proboscis motor neuron","ru":"MN9 — моторный нейрон хоботка"},"side":"right","hz":12.7}],"by_class":{"descending":57,"sensory":20,"central":168,"motor":18,"visual_centrifugal":2,"ascending":2},"bytes":42792},{"id":"jon","icon":"🪶","rate":220,"label":{"en":"Antenna touched","ru":"Антенну задели"},"what":{"en":"145 Johnston’s organ neurons — the antenna’s mechanosensors","ru":"145 нейронов Джонстонова органа — механорецепторы антенны"},"expect":{"en":"A real fly cleans its antennae with its front legs. In the model the grooming descending neurons aDN1 and aBN1 fire.","ru":"У мухи — чистка антенн передними лапами. В модели зажигаются нисходящие нейроны груминга aDN1 и aBN1."},"stim":145,"active":776,"spikes":43654,"trials":10,"ignited":0,"top":[{"i":1703,"type":"CB1231b","cls":"central","side":"left","hz":208.5},{"i":4278,"type":"CB1231b","cls":"central","side":"left","hz":193.2},{"i":1206,"type":"CB1231b","cls":"central","side":"left","hz":179.8},{"i":34621,"type":"CB1231b","cls":"central","side":"left","hz":155.1},{"i":26088,"type":"DNg84","cls":"descending","side":"left","hz":146.5},{"i":34169,"type":"CB0307","cls":"central","side":"left","hz":140.3},{"i":30006,"type":"CB3912","cls":"central","side":"left","hz":139.3},{"i":34204,"type":"CB1231b","cls":"central","side":"left","hz":123.5},{"i":36735,"type":"CB0591","cls":"central","side":"left","hz":122.2},{"i":8823,"type":"SAD076","cls":"central","side":"left","hz":120.8},{"i":250,"type":"DNg29","cls":"descending","side":"left","hz":113.9},{"i":39989,"type":"AN_GNG_65","cls":"ascending","side":"left","hz":111.7},{"i":31556,"type":"CB1231a","cls":"central","side":"left","hz":110.5},{"i":35439,"type":"CB1125","cls":"central","side":"left","hz":107.4}],"keys":[{"i":35318,"kind":"aDN1","label":{"en":"aDN1 — grooming descending neuron","ru":"aDN1 — нисходящий нейрон груминга"},"side":"right","hz":33.7},{"i":37519,"kind":"aDN2","label":{"en":"aDN2 — grooming descending neuron","ru":"aDN2 — нисходящий нейрон груминга"},"side":"right","hz":32.9},{"i":13434,"kind":"aBN1","label":{"en":"aBN1 — antennal grooming neuron","ru":"aBN1 — нейрон чистки антенн"},"side":"left","hz":68.3}],"by_class":{"sensory":145,"central":431,"optic":14,"descending":146,"ascending":16,"motor":8,"visual_centrifugal":9,"visual_projection":7},"bytes":272140},{"id":"looming","icon":"🫥","rate":150,"label":{"en":"Something’s coming","ru":"Что-то летит"},"what":{"en":"50 LC4 neurons of the right eye — detectors of an approaching object","ru":"50 нейронов LC4 правого глаза — детекторы надвигающегося объекта"},"expect":{"en":"A looming shadow means escape. LC4 hand the signal to the giant fiber (DNp01), the command neuron of the jump.","ru":"Надвигающаяся тень — сигнал к бегству. LC4 передают его на гигантское волокно (DNp01), командный нейрон прыжка."},"stim":50,"active":523,"spikes":17586,"trials":10,"ignited":0,"top":[{"i":36175,"type":"DNp04","cls":"descending","side":"right","hz":239.5},{"i":36628,"type":"PVLP010","cls":"central","side":"right","hz":208.8},{"i":30764,"type":"PVLP024","cls":"central","side":"right","hz":195.8},{"i":33057,"type":"PVLP024","cls":"central","side":"right","hz":190.2},{"i":35065,"type":"PVLP130","cls":"central","side":"right","hz":181.2},{"i":8341,"type":"DNp02","cls":"descending","side":"right","hz":181.0},{"i":9097,"type":"PVLP021","cls":"central","side":"right","hz":145.3},{"i":6598,"type":"DNp11","cls":"descending","side":"right","hz":142.1},{"i":27199,"type":"AMMC-A1","cls":"central","side":"right","hz":140.3},{"i":26624,"type":"PVLP011","cls":"central","side":"left","hz":137.9},{"i":32860,"type":"PVLP022","cls":"central","side":"right","hz":137.9},{"i":2619,"type":"CB3885","cls":"central","side":"center","hz":132.9},{"i":34827,"type":"DNp05","cls":"descending","side":"right","hz":124.1},{"i":36900,"type":"DNp01","cls":"descending","side":"right","hz":122.0}],"keys":[{"i":36900,"kind":"DNp01","label":{"en":"DNp01 — giant fiber, the jump","ru":"DNp01 — гигантское волокно, прыжок"},"side":"right","hz":122.0},{"i":36901,"kind":"DNp01","label":{"en":"DNp01 — giant fiber, the jump","ru":"DNp01 — гигантское волокно, прыжок"},"side":"left","hz":31.5}],"by_class":{"visual_projection":63,"central":288,"optic":68,"descending":73,"visual_centrifugal":23,"motor":8},"bytes":113708},{"id":"geosmin","icon":"🍄","rate":40,"label":{"en":"Mould","ru":"Плесень"},"what":{"en":"39 DA2 receptors — geosmin, the smell of dangerous mould","ru":"39 рецепторов DA2 — геосмин, запах опасной плесени"},"expect":{"en":"The textbook innate-aversion pathway: receptors → DA2 projection neurons → lateral horn neurons LHAV2d1 and LHAD1f2. Only 40 Hz: at 60 Hz the model already runs away, see “Runaway”.","ru":"Учебниковый путь врождённого отвращения: рецепторы → проекционные нейроны клубочка DA2 → нейроны латерального рога LHAV2d1 и LHAD1f2. Частота всего 40 Гц: на 60 Гц модель уже срывается, см. «Срыв»."},"stim":39,"active":53,"spikes":1604,"trials":8,"ignited":2,"top":[{"i":31342,"type":"DA2_lPN","cls":"central","side":"right","hz":18.6},{"i":32268,"type":"DA2_lPN","cls":"central","side":"right","hz":18.4},{"i":32922,"type":"DA2_lPN","cls":"central","side":"right","hz":17.1},{"i":32813,"type":"DA2_lPN","cls":"central","side":"right","hz":13.8},{"i":6044,"type":"DA2_lPN","cls":"central","side":"right","hz":9.8},{"i":2717,"type":"lLN2P_a","cls":"central","side":"right","hz":4.1},{"i":32086,"type":"DA2_lPN","cls":"central","side":"right","hz":3.2},{"i":33518,"type":"LHAV2d1","cls":"central","side":"right","hz":2.2},{"i":36776,"type":"lLN2T_b","cls":"central","side":"right","hz":1.6},{"i":8056,"type":"lLN2P_c","cls":"central","side":"right","hz":1.4},{"i":36891,"type":"lLN2F_b","cls":"central","side":"right","hz":0.6},{"i":32075,"type":"DA2_lPN","cls":"central","side":"left","hz":0.2},{"i":31752,"type":"DA2_lPN","cls":"central","side":"left","hz":0.2},{"i":38245,"type":"LHAD1f2","cls":"central","side":"right","hz":0.1}],"keys":[{"i":31342,"kind":"DA2","label":{"en":"DA2 lPN — geosmin projection neuron","ru":"DA2 lPN — проекционный нейрон геосмина"},"side":"right","hz":18.6},{"i":32268,"kind":"DA2","label":{"en":"DA2 lPN — geosmin projection neuron","ru":"DA2 lPN — проекционный нейрон геосмина"},"side":"right","hz":18.4},{"i":33518,"kind":"LHAV2d1","label":{"en":"LHAV2d1 — lateral horn, innate responses","ru":"LHAV2d1 — латеральный рог, врождённые реакции"},"side":"right","hz":2.2},{"i":8451,"kind":"LHAV2d1","label":{"en":"LHAV2d1 — lateral horn, innate responses","ru":"LHAV2d1 — латеральный рог, врождённые реакции"},"side":"left","hz":0.0}],"by_class":{"sensory":39,"central":14},"bytes":14056},{"id":"runaway","icon":"🌀","rate":150,"label":{"en":"Runaway","ru":"Срыв"},"what":{"en":"the same 162 vinegar receptors, but at 150 Hz like the tastes","ru":"те же 162 рецептора уксуса, но на 150 Гц — как вкусы"},"expect":{"en":"The model blows up: within 16 ms the wave takes over ~10,000 neurons — every Kenyon cell, the whole antennal lobe — and everything fires at the limit. Vinegar, mould, CO₂, heat, cold and humidity all end in the same state. Vinegar runs away even at 5 Hz — below what real receptors fire. Real flies don’t do this: the model has no neuronal adaptation and no inhibition at the synapses themselves. This is the edge of what wiring without physiology can do.","ru":"Модель срывается в разнос: за 16 мс волна захватывает ~10 000 нейронов — все клетки Кеньона, весь антеннальный отдел, — и дальше всё горит на пределе. Уксус, плесень, CO₂, жара, холод и влажность приводят в одно и то же состояние. Уксус срывается даже на 5 Гц — ниже, чем стреляют настоящие рецепторы. У живой мухи так не бывает: в модели нет адаптации нейронов и торможения на самих синапсах. Это граница того, что умеет схема без физиологии."},"stim":162,"active":10613,"spikes":873302,"trials":10,"ignited":0,"top":[{"i":36897,"type":"APL","cls":"central","side":"left","hz":430.0},{"i":3057,"type":"APL","cls":"central","side":"right","hz":429.5},{"i":16390,"type":"DPM","cls":"central","side":"left","hz":424.5},{"i":2544,"type":"il3LN6","cls":"central","side":"right","hz":414.3},{"i":36805,"type":"il3LN6","cls":"central","side":"left","hz":413.5},{"i":36855,"type":"v2LN30","cls":"central","side":"right","hz":413.1},{"i":36759,"type":"lLN1_bc","cls":"central","side":"right","hz":413.0},{"i":931,"type":"lLN1_bc","cls":"central","side":"left","hz":413.0},{"i":1536,"type":"lLN1_bc","cls":"central","side":"left","hz":413.0},{"i":36629,"type":"lLN1_bc","cls":"central","side":"left","hz":413.0},{"i":33097,"type":"lLN1_bc","cls":"central","side":"left","hz":413.0},{"i":36672,"type":"lLN1_bc","cls":"central","side":"left","hz":413.0},{"i":36529,"type":"lLN1_bc","cls":"central","side":"left","hz":413.0},{"i":36741,"type":"v2LN30","cls":"central","side":"left","hz":413.0}],"keys":[],"by_class":{"central":9117,"sensory":895,"descending":208,"ascending":8,"optic":278,"visual_centrifugal":61,"visual_projection":40,"motor":6},"bytes":1048564},{"id":"light","icon":"💡","rate":100,"label":{"en":"Flash","ru":"Вспышка"},"what":{"en":"1,320 R7 and R8 photoreceptors of the right eye","ru":"1 320 фоторецепторов R7 и R8 правого глаза"},"expect":{"en":"Here the model honestly fails: the wave barely gets past the first medulla cells. Photoreceptors use histamine, and FlyWire’s neural network predicts only six transmitters — histamine isn’t one of them. That’s why Eon used the separately trained flyvis model for vision.","ru":"Здесь модель честно не справляется: волна почти не уходит дальше первых клеток медуллы. Фоторецепторы работают на гистамине, а нейросеть FlyWire угадывает только шесть медиаторов, и гистамина среди них нет. Поэтому для зрения Eon брали отдельную обученную модель flyvis."},"stim":1320,"active":1387,"spikes":132077,"trials":10,"ignited":0,"top":[{"i":127971,"type":"Dm9","cls":"optic","side":"right","hz":77.0},{"i":127598,"type":"Dm9","cls":"optic","side":"right","hz":71.4},{"i":128161,"type":"Dm9","cls":"optic","side":"right","hz":58.8},{"i":112802,"type":"Dm9","cls":"optic","side":"right","hz":36.5},{"i":127174,"type":"Dm9","cls":"optic","side":"right","hz":34.9},{"i":127802,"type":"Dm9","cls":"optic","side":"right","hz":33.4},{"i":63167,"type":"DmDRA1","cls":"optic","side":"right","hz":31.1},{"i":79995,"type":"DmDRA1","cls":"optic","side":"right","hz":30.6},{"i":8288,"type":"MeMe_e10","cls":"optic","side":"right","hz":30.2},{"i":127150,"type":"Dm9","cls":"optic","side":"right","hz":28.5},{"i":62401,"type":"DmDRA2","cls":"optic","side":"right","hz":24.3},{"i":137154,"type":"Dm9","cls":"optic","side":"right","hz":24.3},{"i":119760,"type":"Dm9","cls":"optic","side":"right","hz":22.9},{"i":137299,"type":"Dm9","cls":"optic","side":"right","hz":20.9}],"keys":[],"by_class":{"visual_projection":2,"optic":65,"sensory":1320},"bytes":807568}]